Bio Break: Tooth-In-Eye Surgery

Resources

Bio Break: Tooth-In-Eye Surgery

Sector: Surgical
Topic: Bio Break

In this episode of Bio Break, Nick Allan and Joris van der Heijden dive into one of the most astonishing medical innovations we’ve ever come across: osteo-odonto-keratoprosthesis. Or, as Nick quickly dubs it, “tooth in eye surgery.”

This fascinating procedure sounds like science fiction but has been successfully used to restore vision in people who are blind due to damage in the front part of the eye, such as from trauma or autoimmune diseases. While the retina remains functional, traditional options are off the table. That’s where this extreme innovation comes in.

Joris explains how the procedure starts with removing a patient’s tooth and some surrounding bone to create a small square-shaped structure. A hole is drilled in the center, and a tiny lens is implanted, this piece will eventually act as an artificial cornea. But before it’s implanted into the eye, it needs to be biologically prepared. That’s done by temporarily placing the implant into the patient’s cheek, where it can become vascularized over a few months.

Once ready, the patient returns to the hospital for the second stage. Surgeons retrieve the now-living implant from the cheek and carefully insert it into the eye, replacing the damaged corneal area. Thanks to the previously grafted oral tissue, the eye is prepped to accept the implant, and the result is stunning: restored vision in up to 90% of patients.

Even more impressive? Around 50% of these individuals gain high-quality vision, enough to read or even consider driving.

Whether you’re a medtech enthusiast or just love mind-blowing medical stories, this episode is a must-watch. Learn how combining dental tissue, ocular surgery, and a bit of clever biology can give people their sight back.

Tooth-In-Eye Surgery

Cropped photo of qualified doctor estimating amount of oxygen in patient blood

If you’ve ever been to the hospital, you’ll know that one of the first things hospital staff do is attach “that finger clip device” to your finger. “That device” is called a Pulse Oximeter, and it provides information on pulse rate and blood oxygenation.

Fluorescent Imaging immunofluorescence of cancer cells growing in 2D with nuclei in blue, cytoplasm in red and DNA damage foci in green

Fluorescence Imaging in Medical Devices outlines medical applications and examples of devices that use fluorescence for imaging.

A composite image showing an eye processed through a sequence of transformations from left to right. The leftmost section displays a relatively clear image of a human eye with natural textures and lashes. Moving right, the image becomes increasingly abstract and pixelated through various digital processing techniques, including edge detection, binarization, contrast enhancement, and pixel block reduction. Each vertical segment represents a different stage or algorithm in the image processing pipeline, transitioning from high-resolution realism to low-resolution abstraction.

Computer Vision for Medical Devices is constantly evolving and incorporating new techniques and technologies as they emerge.

A macro shot of a 3D bioprinter depositing layers of bioink to create tissue constructs for medical research, Bioprinting technology style, photo of

Being able to control the release rate of a target molecule is a valuable tool for engineering tissues and therapeutic delivery of regenerative medicine applications.