Radiopharmaceutical Device Development Explained

Two men, Nick A. (left) and Nigel (right), sit at a white table, engaging in a lively and friendly conversation. Both wear checkered shirts and lavalier microphones, suggesting a filmed discussion or interview. Nick holds tissue samples in one hand and gestures animatedly, while Nigel smiles in response. Each has a white mug labeled with their name and a purple star logo. The background is a bright white, creating a clean and professional studio setting.
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Radiopharmaceutical Device Development Explained

Sector: Diagnostics
Topic: Bio Break
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Radiopharmaceutical device development is gaining momentum as medical teams explore new frontiers in diagnostic imaging and cancer treatment. In this episode of Bio Break, Nigel and Nick dive into how radioisotopes are used in both therapeutic and imaging applications—and what it means for engineers designing devices that handle radiation safely.

Nigel explains how these radioactive compounds—like radiolabeled glucose—can help detect cancer by highlighting areas of high metabolic activity in the body. The technique is based on how tumors often consume more glucose than surrounding tissue. So when tagged with a tracer like FDG (fluorodeoxyglucose), those hotspots become visible.

Nick shares his own experience using these radiopharmaceuticals in drug delivery trials. He describes a study comparing radiolabeled compounds that either do or do not cross the blood-brain barrier. By using FDG as a positive control and FLT (fluorothymidine) as a negative control, his team was able to track how a drug reached—or failed to reach—the brain.

As device developers, the implications are clear. Designing tools that safely handle radioactive materials requires special care. From the initial generator to the final “daughter” isotopes used in patients, radiopharmaceutical workflows are complex, fast-moving, and full of potential.

For medical device innovators, this space offers exciting opportunities—especially as demand for targeted therapies and precise imaging continues to grow.

Learn more about StarFish Medical.

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