Device Repurposing in Research

Two men, Nick A. (left) and Nigel (right), sit at a white table, engaging in a lively and friendly conversation. Both wear checkered shirts and lavalier microphones, suggesting a filmed discussion or interview. Nick holds tissue samples in one hand and gestures animatedly, while Nigel smiles in response. Each has a white mug labeled with their name and a purple star logo. The background is a bright white, creating a clean and professional studio setting.
Resources

Device Repurposing in Research

Sector: Diagnostics
Topic: Bio Break
YouTube video thumbnail

How adapting existing tools can drive innovation

In this episode of Bio Break, Nick Allan and Nigel Syrotuck discuss device repurposing in research, sharing a story that blends microbiology, animal science, and engineering ingenuity. The episode begins with Nick examining an unusual medical device originally used for equine reproductive sampling. As Nigel jokes about its “unique” application, Nick explains how his team repurposed the tool to study bovine respiratory diseases during the COVID era.

The conversation highlights how adaptability is key in research. During supply shortages, Nick’s team used what they had—an equine sampling instrument—to collect deep nasal swabs from cattle for studying Mycoplasma bovis. This creative approach reflects the practical side of device repurposing in research: using proven, sterile, and available tools to advance science quickly and safely.

From animal care to microbiology

Nigel and Nick explore how one device can serve multiple disciplines when handled thoughtfully. Engineers often design instruments for a single, specific purpose. However, researchers in both human and veterinary medicine sometimes find safe, responsible ways to apply existing devices in new contexts. This not only saves time and cost but also helps teams continue important studies despite logistical barriers.

Engineering meets resourcefulness

As Nigel points out, clinicians and engineers must sometimes foresee off-label uses or modifications. Understanding these adaptations helps teams ensure safety while maintaining design integrity. The story reminds us that innovation doesn’t always start from scratch—sometimes it comes from seeing familiar tools in a new way.

By the end, both hosts emphasize that flexibility and informed adaptation can lead to new discoveries, whether in animal health or medical device design.

Indirect ELISA explained with antibody model showing enzyme linked immunoassay detection

Nick and Nigel walk through how indirect ELISA works, why it uses two antibodies instead of one, and when this approach makes the most sense in real diagnostic workflows.

Smartwatch displaying heart rate and ECG-style waveform, illustrating the difference between wellness devices and medical devices in digital health regulation

Ariana Wilson and Mark Drlik break down medical vs wellness devices and explain why two products with identical hardware can fall into completely different regulatory categories.

Nick from StarFish Medical demonstrating antigen detection using a toy antibody model to explain how monoclonal antibodies bind antigens in ELISA diagnostics

Nick and Nigel break down the ELISA assay explained in simple, practical terms using everyday models.

Magnifying glass revealing cracks with the text “This gets missed,” illustrating hidden risks in medical device validation and real-world use.

Ariana Wilson sits down with Mark Drlik to unpack why reprocessing is often one of the hardest challenges engineers face during development.