Accommodative Intraocular Lens Technology Explained

MedDevice by Design with Mark Drlik and Ariana Wilson
Resources

Accommodative Intraocular Lens Technology Explained

YouTube video thumbnail

In this episode of MedDevice by Design, Ariana and Mark explore how accommodative intraocular lens technology may one day restore natural vision for people who require cataract surgery or suffer from presbyopia. As Mark shares, traditional bifocals are not ideal, and new lens solutions may offer better outcomes.

What Is an Accommodative Intraocular Lens?

When cataract surgery is performed, the natural lens of the eye is typically replaced with a hard plastic lens. Unfortunately, this artificial lens lacks the ability to focus on both near and far objects. An accommodative intraocular lens seeks to solve this problem by mimicking the eye’s natural focusing ability. The lens responds to the eye’s ciliary muscles, allowing it to adjust its shape and focal distance, similar to a healthy, youthful eye.

The Challenge of Developing These Lenses

Currently, most accommodative lenses on the market fall short of fully restoring accommodation. Mark mentions products like Crystalens, which offer some adjustment but not enough for full reading and distance vision without glasses. For many patients, achieving about 1.5 diopters of accommodation is still a challenge. This technical hurdle makes developing a truly effective accommodative intraocular lens complex.

Market Demand and Development Pipeline

As discussed, the market for intraocular lens implants is large and well-established, creating a strong business case. Several companies are actively working on next-generation accommodative intraocular lenses. Mark mentions companies like LensGen, JellySea, Omniview, FluidVision, Synchrony, and TiaVision, all working through clinical studies. However, none have reached full FDA clearance yet.

Why This Lens Technology Matters

Accommodative intraocular lenses offer significant potential to improve quality of life for millions of patients who want to reduce or eliminate their dependence on glasses after cataract surgery. While regulatory pathways and technical feasibility remain hurdles, these emerging devices continue to generate strong interest across the ophthalmology community.

Gloved hands handling a pharmaceutical vial through a shielded enclosure, illustrating the manual theranostics delivery workflow discussed in a Bio Break episode

Theranostics combines diagnosis and therapy into a single targeting system, using one ligand to attach to two different radioactive payloads, one for imaging and one for treatment. It represents a significant shift in how cancer is being identified and treated. But the theranostics delivery workflow tells a different story.

Home use medical device usability challenges for a lay user managing a monitoring device at home

Most medical devices were designed for clinical settings, not the patients and caregivers who increasingly rely on them at home. Here’s what good home-use device design actually requires.

Comfort evaluation in medical device design showing researcher recording observations while assessing wearable device fit on a participant's wrist

How do you measure comfort in medical device design? Explore the tools, scales, and study design principles that turn a subjective experience into actionable design data.

Woman checking smartwatch health data UX design with concerned expression after waking, illustrating how poorly framed health metrics cause anxiety

Gathering health data has enormous value for spotting risks, improving care, and advancing science. The problem isn’t capturing the data. The problem is how we choose to present it and who we’re really serving when we do.